Correlation between Sperm Parameters and Sperm DNA Fragmentation in Fertile and Infertile Cigarette Smoking Patients

The present study to investigate that the correlation between sperm parameters and sperm DNA fragmentation in fertile and infertile cigarette smoking patient. Forty men undergoing infertility evaluation were divided into four groups according their smoking ability (A: 2 days ( n=10), B: 4 days ( n=10), C: 8 days ( n=10), D: 15 days ( n=10)) sperm parameters ( sperm concentration, pH, Viscosity, sperm count, motility, viability, Leukocyte concentration and comet value) . The comparisons of mean sperm count, motility viability and normal morphology among four different cigarette smoking user groups were statistical significant. Mean sperm motility viability and normal morphology were significantly different in cigarette smoking user groups within two sperm count groups. Use of cigarette smoking decrease the semen quality in men by decreasing the sperm count, motility, viability and normal morphology. The decrease in sperm parameters was dependent on the duration of 2 days exposure to cigarette smoking and independent of the initial semen quality.